announcements
[11/10/08]
Transcriptional study of clostridial differentiation published in Genome Biology
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[11/03/08]
2008 AIChE Annual Meeting Presentations
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[10/23/08]
A global transcriptional view of apoptosis in human T-cell activation
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[06/04/08]
Clostridium acetobutylicum genome-scale model manuscripts published in B&B
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the facilities
The research facilities for the Group are in laboratories in the Delaware Biotechnology Institute, which is a state-of-the art research facility for modern research in the biological sciences and bioengineering.
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Genomics, systems & synthetic biology, and metabolic engineering applied to stem-cell bioengineering and biorefining. The Papoutsakis Group focuses on the study and modification of regulatory networks that control key cellular programs such as stem-cell differentiation and plasticity or prokaryotic sporulation and stationary-phase phenomena. This research contributes to the understanding of cellular processes of both fundamental and industrial interests—such as stem-cell bioengineering or the link between sporulation, solvent production and stress response in solventogenic clostridia for biofuel production and biorefinery applications—and involves interdisciplinary work in the areas of systems biology, metabolic engineering, experimental and computational genomics, stem-cell biology, and hematology. By combining state-of-the-art microarray and genomic analysis techniques with molecular biological tools and cellular physiology, the Papoutsakis Group aims to unravel the exquisitely crafted interplay of cellular processes that allow the exploration of cells for beneficial applications from Regenerative Medicine to Industrial Biotechnology.
the group
The Papoutsakis Research Group is an active, vibrant and collaborative team of educators, students, researchers and scientists. The group is comprised of PhD and other graduate students, postdoctoral fellows, a lab manager, undergraduate and visiting students, occasionally visiting scientists, and Papoutsakis’ administrative coordinator. Our mission is to carry out world-class, forward-looking, genomic-based research in the context of bioengineering, biochemical engineering and more broadly modern biology. Based at the Delaware Biotechnology Institute at the University of Delaware, the Papoutsakis Research Group is dedicated to initiating and supporting the best of front line research and technology within the ever-changing and wide-ranging scope of the molecular life sciences.
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