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T-Cell Bioengineering & Genomics

150. Carswell, K. S., and Papoutsakis, E. T., "Culture of human T-cells in stirred bioreactors for cellular immunotherapy applications: shear, proliferation, and the IL-2 receptor", Biotechnol. Bioeng. 68: 328-338 (2000).(Download PDF)

151. Carswell, K. S., Weiss, J. W. and Papoutsakis, E. T., "Low oxygen tension enhances the stimulation and proliferation of human T lymphocytes", Cytotherapy. 2: 25-37 (2000).(Download PDF)

157. Carswell, K. S., and Papoutsakis, E. T., "Extracellular pH affects the proliferation of cultured human T-cells and their expression of the interleukin 2 receptor", J. Immunotherapy. 23: 669-674 (2000).

161. Haddad, H, Carswell, K. S., and Papoutsakis, E. T., "Ex vivo expansion of Human T lymphocytes", in Methods in Tissue Engineering (A. Atala & R. Lanza, Eds.), Academic Press, San Diego. Chapter 41: pp. 487-502 (2002).

162. Haddad, H, and Papoutsakis, E. T., "Low oxygen tension and autologous plasma increase T-cell proliferation in serum-free media", Cytotherapy. 3: 435-447 (2001).

169. Yang, H., Haddad, H., Tomas, C., Alsaker, K., and Papoutsakis E. T., "A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis", Proc. Nat. Acad. Sci. (USA). 100: 1122-1127 (2003).(Download PDF)

177. Haddad-Adams, H, Windgassenc D., Ramsborg, C. G., Paredes, C., and Papoutsakis, E. T., "Molecular understanding of oxygen-tension and patient-variability effects on Ex vivo expanded T-cells", Biotechnol. Bioeng. 87: 437-450 (2004).(Download PDF)

180. Ramsborg CG, D. Windgassen, C. J. Paredes and E. T. Papoutsakis, "Molecular insights into the pleiotropic effects of plasma on Ex vivo expanded T-cells using DNA-microarray analysis", Exp. Hematol. 32: 970-990 (2004).(Download PDF)

195 . Ramsborg CG and E. T. Papoutsakis, "Global transcriptional analysis delineates the differential inflammatory response interleukin-15 elicits from cultured human T cells", Exp. Hematol. 35: 454-464 (2007).

209. Wang M, Windgassen D, Papoutsakis ET. "Comparative analysis of transcriptional profiling of CD3+, CD4+ and CD8+ T cells indentifies novel immune response players in T-cell activaiton" BMC Genomics. 2008 May 16;9(1):225

211. Wang, M., Windgassen, D., and Papoutsakis, E.T. 2008. Comparative Analysis of Transcriptional Profiling of CD3+, CD4+ and CD8+ T cells Identifies Novel Immune Response Players in T-Cell Activation. BMC Genomics. 16:9(1):225. (Download PDF)

212. Wang, M., Windgassen, D., and Papoutsakis, E.T. 2008. A Global Transcriptional View of Apoptosis in Human T-Cell Activation. BMC Medical Genomics 1:53 doi:10.1186/1755-8794-1-53. (Download PDF)