1978 - 1989

1. Papoutsakis, E., Lim, H.C. and Tsao, G.T., "Role of formaldehyde in the utilization of C1-compounds via the ribulose monophosphate cycle", Biotechnol. Bioeng. 20: 421-442 (1978). (Download PDF)

2. Papoutsakis, E., Lim, H.C. and Tsao, G.T., "SCP production on C1 compounds", AIChE J. 24: 406-417 (1978).(Download PDF)

3. Hirt, W., Papoutsakis, E., Krug, E., Lim, H.C. and Tsao, G.T., "Formaldehyde incorporation by a new methylotroph (L3)", Appl. Environ. Microbiol. 36: 56-62 (1978). (Download PDF)

4. Papoutsakis, E., Ramkrishna, D. and Lim, H.C., "The extended Graetz problem with Dirichlet wall boundary conditions", Appl. Sci. Res. 36: 13-34 (1980).

5. Papoutsakis, E., Ramkrishna, D. and Lim, H.C., "The extended Graetz problem with prescribed wall flux", AIChE J. 26: 779-787 (1980).(Download PDF)

6. Papoutsakis, E., Hirt, W. and Lim, H.C., "On the Bacterial utilization of pure and mixed C1 compounds for SCP production", Biotechnol. Bioeng., 23: 235-242 (1981).(Download PDF)

7. Papoutsakis, E. and Ramkrishna, D., "Conjugated Graetz problems. I. General formalism and a class of solid-fluid problems", Chem. Eng. Sci. 36: 1381-1391 (1981).(Download PDF)

8. Papoutsakis, E. and Ramkrishna, D., "Conjugated Graetz problems. II. Fluid-fluid problems", Chem. Eng. Sci. 36: 1393-1399 (1981).

9. Papoutsakis, E. and Ramkrishna, D., "Heat transfer in a capillary flow emerging from a reservoir", Trans. ASME, J. Heat Transf. 103: 429-435 (1981).

10. Papoutsakis, E., "Nusselt numbers near the entrance of the heat-exchange section in flow systems", AIChE J. 27: 687-689 (1981). (Download PDF)

11. Papoutsakis, E. and Lim, H.C., "SCP production on C1 compounds: the bioefficiency", Ind. Eng. Chem. Fundam. 20: 307-314 (1981).(Download PDF)

12. Papoutsakis, E.T., "A Useful equation for fermentations of butyric-acid bacteria", Biotechnol. Lett. 5: 253-258 (1983).(Download PDF)

13. Diwan, A.R., Chu, I-M. and Papoutsakis E.T., "Substrate transport and its effect on the dynamics of methylotrophic growth", Biotechnol. Lett. 5: 579-584 (1983).

14. Papoutsakis, E.T., "A useful equation for fermentations of butyric-acid bacteria. Scenarios for controls of solvent production", in The Acetone-Butanol Fermentation and Related Topics, J.D. Bu'Lock and A.J. Bu'Lock, Eds. (Science and Technology Letters, London, 1983), Fermentation Research I, pp. 121-128.

15. Papoutsakis, E.T., "Equations and calculations for fermentations of butyric acid bacteria", Biotechnol. Bioeng. 26: 174-187 (1984).(Download PDF)

16. Papoutsakis, E.T. and Meyer, C.L., "Equations and calculations of product yields and preferred pathways for butanediol and mixed-acid fermentations", Biotechnol. Bioeng. 27: 50-66 (1985).(Download PDF)

17. Papoutsakis, E.T. and Meyer, C.L., "Fermentation equations for propionic- acid bacteria and for production of assorted oxychemicals from various sugars", Biotechnol. Bioeng. 27: 67-80 (1985).(Download PDF)

18. Chu, I-M. and Papoutsakis, E.T., "Carbon oxidation and incorporation patterns in batch cultures of Methylomonas L3" Biotechnol. Lett. 7, 15-20 (1985).(Download PDF)

19. Meyer, C.L., McLaughlin, J.K. and Papoutsakis, E.T., "The effect of CO on growth and product formation in batch cultures of Clostridium acetobutylicum", Biotechnol. Lett., 7: 37-42 (1985).(Download PDF)

20. Roos, J.W., McLaughlin, J.K. and Papoutsakis, E.T., "The effect of pH on nitrogen supply, biomass lysis and solvent production in fermentations of Clostridium acetobutylicum", Biotechnol. Bioeng. 27: 681-694 (1985).(Download PDF)

21. McLaughlin, J.K., Meyer, C.L. and Papoutsakis, E.T., "Gas chromatography and gateway sensors for on-line state estimation of complex fermentations (Butanol/Acetone Fermentation)", Biotechnol. Bioeng. 27: 1246-1257 (1985).(Download PDF)

22. Chu, I-M., Bussineau, C.M. and Papoutsakis, E.T., "Direct measurement of carbon-substrate oxidation and incorporation patterns in RuMP-Type methylotrophs. Chemostatic cultures of Methylomonas L3", Biotechnol. Bioeng. 27: 1623-1633 (1985).(Download PDF)

23. Huesemann, M., and Papoutsakis, E.T., "Effect of acetoacetate, butyrate, and uncoupling ionophores on growth and product formation of Clostridium acetobutylicum", Biotechnol. Lett. 8: 37-42 (1986).

24. Meyer, C.L., McLaughlin, J.K. and Papoutsakis, E.T., "On-line chromatographic analysis and fermentor state characterization of butanol/acetone fermentations", Biochemical Engineering IV, Ann. N.Y. Acad. Sci., 469: 350-363 (1986).

25. Cherry, R.S. and Papoutsakis, E.T., "Hydrodynamic effects on cells in agitated tissue culture reactors", Bioproc. Eng. 1: 29-41 (1986).

26. Meyer, C.L., Roos, J.W. and Papoutsakis, E.T., "Carbon monoxide gasing leads to alcohol production and butyrate uptake without acetone formation in continuous cultures of Clostridium acetobutylicum", Appl. Microbiol. Biotechnol. 24: 159-167 (1986).

27. Bussineau, C.M. and Papoutsakis, E.T., "Intracellular reaction rates, enzyme activities and biomass yields in Methylomonas L3: Growth rate and substrate-composition effects", Appl. Microbiol. Biotechnol. 24: 435-442 (1986).(Download PDF)

28. Chu, I-M. and Papoutsakis, E.T., "Growth dynamics of a methylotroph (Methylomonas L3) in continuous cultures. I. Fast transients induced by methanol pulses and methanol accumulation", Biotechnol. Bioeng. 29: 55-64 (1987).(Download PDF)

29. Chu, I-M. and Papoutsakis, E.T., "Growth dynamics of a methylotroph (Methylomonas L3) in continuous cultures. II. Growth inhibition and comparison against an unstructured model", Biotechnol. Bioeng. 29: 65-71 (1987).

30. Bussineau, C.M., Keuer, T.A., Chu, I-M. and Papoutsakis, E.T., "Effect of growth conditions on enzyme activities, intracellular kinetics and biomass yields of a new RuMP-Type methylotroph (T15)", Appl. Microbiol. Biotechnol. 26: 61-69 (1987). (Download PDF)

31. Chu, I-M., Keuer, T.A. and Papoutsakis, E.T., "Formate transport, growth inhibition and the membrane protonmotive force in two methylotrophs (T15 and L3)", Appl. Microbiol. Biotechnol. 26: 70-77 (1987). (Download PDF)

32. Papoutsakis, E.T., Bussineau, C.M., Chu, I-M., Diwan, A.R. and Huesemann, M., "Transport of substrates and metabolites and their effect on cell metabolism [in butyric-acid and methylotrophic fermentations]", Biochem. Engineering V, Ann. N.Y. Acad. Sci. 506: 24-50 (1987).

33. Bussineau, C.M. and Papoutsakis, E.T., "Evidence suggesting energy-dependent formaldehyde transport in an RuMP-type methylotroph (T15)", Arch. Microbiol. 149: 214-219 (1988).(Download PDF)

34. Meyer, C.L. and Papoutsakis, E.T., "Detailed stoichiometry and process analysis" In: Handbook on Anaerobic Fermentations (L.E. Erickson, D.Y.C. Fung, eds.) Chp. 4, pp. 83-118, Marcel Dekker, N.Y. (1988).

35. San, K-Y., Papoutsakis, E.T. and Stephanopoulos, G.N., "Measurement, data analysis, and control", pp. 441-462, Chp. 14 in Handbook on Anaerobic Fermentations (L.E. Erickson, D.Y.C. Fung, eds) Marcel Dekker, N.Y. (1988).

36. Cherry, R.S. and Papoutsakis, E.T., "Physical mechanisms of cell damage in microcarrier cell culture bioreactors", Biotechnol. Bioeng. 32: 1001-1014 (1988).(Download PDF)

37. Huesemann, M.H.W. and Papoutsakis, E.T., "Solventogenesis in Clostridium acetobutylicum fermentations related to carboxylic acid and proton concentrations", Biotechnol. Bioeng. 32: 843-852 (1988).(Download PDF)

38. Petersen, J.F., McIntire, L.V. and Papoutsakis, E.T., "Shear sensitivity of cultured hybridoma cells (CRL-8018) depends on mode of growth, culture age and metabolite concentration", J. Biotechnol. 7: 229-246 (1988).(Download PDF)

39. Cary, J.W., Petersen, D.J., Papoutsakis, E.T., and G.N. Bennett," Cloning and expression of Clostridium acetobutylicum phosphotransbutyrylase and butyrate kinase genes in Escherichia coli", J. Bacteriol. 170: 4613-4618 (1988).(Download PDF)

40. Wiesenborn, D.P. Rudolph, F.B., and E.T. Papoutsakis, "Thiolase from Clostridium acetobutylicum ATCC 824 and its role in the synthesis of acids and solvents", Appl. Environ. Microbiol. 54: 2717-2722 (1988).(Download PDF)

41. Wiesenborn, D.P., Rudolph, F.B. and Papoutsakis, E.T., "Phosphotransbutyrylase from Clostridium acetobutylicum ATCC 824 and its role in acidogenesis ", Appl. Environ. Microbiol. 55: 317-322 (1989).(Download PDF)

42. Wiesenborn, D.P., Rudolph, F.B. and Papoutsakis, E.T., "Coenzyme A transferase from Clostridium acetobutylicum ATCC 824 and its role in the uptake of acids", Appl. Environ. Microbiol. 55: 323-329 (1989).(Download PDF)

43. Papoutsakis, E.T. "Acetone-Butanol Fermentation", Chapter 2.1.3 in Biomass Handbook (C.W. Hall, O. Kitani, eds.), Gordon and Breach Publishers, pp. 271-286 (1989).

44. Cherry, R.S. and Papoutsakis, E.T., "Modeling of contact-inhibited animal cell growth on flat surfaces and spheres", Biotechnol. Bioeng. 33: 300-305 (1989).(Download PDF)

45. Meyer, C.L. and Papoutsakis, E.T., "Continuous and biomass recycle fermentations of Clostridium acetobutylicum. Part 1. ATP supply and demand determines product selectivity", Bioproc. Eng. 4: 1-10 (1989).(Download PDF)
46. Meyer, C.L. and Papoutsakis, E.T., "Continuous and biomass recycle fermentations of Clostridium acetobutylicum. Part 2. Novel patterns in energetics and product-formation kinetics", Bioproc. Eng. 4: 49-55 (1989).(Download PDF)

47. Cherry, R.S. and Papoutsakis, E.T., "Growth and death rates of bovine embryonic kidney cells in turbulent microcarrier bioreactors", Bioproc. Eng. 4: 81-89 (1989).(Download PDF)

48. Meyer, C.L. and Papoutsakis, E.T., "Increased levels of ATP and NADH are associated with increased solvent production in continuous cultures of Clostridium acetobutylicum", Appl. Microbiol. Biotechnol. 30: 450-459 (1989).(Download PDF)

49. Huesemann, M.H.W. and Papoutsakis, E.T., "Comparison between in vivo and in vitro enzyme activities in continuous and batch fermentations of Clostridium acetobutylicum", Appl. Microbiol. Biotechnol. 30: 585-595 (1989).(Download PDF)

50. Papoutsakis, E.T. and Kunas, K.T. "Hydrodynamic effects on cultured hybridoma cells CRL 8018 in an agitated bioreactor", in Adv. in Animal Cell Biology and Technology for Bioprocesses. (R. E. Spier et al., eds.). Butterworths. pp. 203-208 (1989).

51. Cary, J.W., Petersen, D.J., Bennett, G.N. and Papoutsakis, E.T. "Methods for cloning key primary metabolic enzymes and ancillary proteins associated with the acetone-butanol fermentation of Clostridium acetobutylicum" Ann. N.Y. Acad. Sci., 589 (Biochem. Engineering VI) (St. Barbara, CA, Oct. 3-7, 1988): 67-81 (1990).

52. Huesemann, M.H.W., and Papoutsakis, E.T., "Enzymes limiting butanol and acetone formation in continuous and batch cultures of Clostridium acetobutylicum", Appl. Microbiol. Biotechnol. 31; 435-444 (1989).(Download PDF)

53. Welch, R.W., Rudolph, F.B. and Papoutsakis, E.T., "Purification and characterization of the NADH dependent butanol dehydrogenase from Clostridum acetobutylicum (ATCC 824)", Arch. Biochem. Biophys. 273: 309-318 (1989).(Download PDF)