220. Alsaker, K.V., Paredes, C. J., & Papoutsakis, E.T. 2010. “Metabolite Stress and Tolerance in the Production of Biofuels and Chemicals: Gene-Expression-Based Systems Analysis of Butanol, Butyrate, and Acetate Stresses in the Anaerobe Clostridium acetobutylicum”, Biotechnol. Bioeng. 105: 1131–1147. DOI 10.1002/bit.22628. (Download PDF)
221. Tracy, BP, Gaida, S.M. and Papoutsakis, ET. Flow cytometry for bacteria: Enabling metabolic engineering, synthetic biology and the elucidation of complex phenotypes. (INVITED). Curr. Opin. Biotechnol. 21:85–99 (2010). DOI: 10.1016/j.copbio.2010.02.006. (Download PDF)
222. Nicolaou, S., Gaida, S. and Papoutsakis, E.T. “A comparative view of metabolite and substrate stress and tolerance in microbial bioprocessing: from biofuels and chemicals, to biocatalysis and bioremediation” Metab. Engin. 12: 307–331 (2010). doi:10.1016/j.ymben.2010.03.004 (Download PDF)
223. Giammona LM, Panuganti S, Kemper JM, Apostolidis PA, Lindsey S, Papoutsakis ET, Miller WM. 2009. Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD(+) levels and SIRT inhibition. Exp. Hematology, 37: 1340-1352. (Download PDF)
224. Panuganti S, Papoutsakis ET, Miller WM. 2010. Bone marrow niche-inspired, multi-phase expansion of megakaryocytic progenitors with high polyploidization potential. 2010. Cytotherapy. 12: 767-782. (Download PDF)
225. Sepúlveda, D.E., Andrews, B.A., Papoutsakis, E.T. and Asenjo, J.A., 2010. Metabolic Flux Analysis of Embryonic Stem Cells Using Three Distinct Differentiation Protocols and Comparison to Gene Expression Patterns. Biotechnol. Progr. 26: 1222-1229. (Download PDF)
226. Wang M, Senger RS, Paredes C, Banik GG, Lin A, & Papoutsakis, ET. 2009. Microarray-Based Gene Expression Analysis as a Process Characterization Tool to Establish Comparability of Complex Biological Products: Scale-Up of a Whole-Cell Immunotherapy Product. Biotechnol. Bioeng. 104: 796-808. (Download PDF)
227. Chen, Y., Indurthi, I., Jones, S. W. and Papoutsakis, E. T. 2011. Small RNAs of the genus Clostridium. mBio 2(1):e00340-10. doi:10.1128/mBio.00340-10. (Download PDF)
228. Lindsey, S. and Papoutsakis, E. T. 2011. The Aryl Hydrocarbon Receptor (AhR) Transcription Factor Regulates Megakaryocytic Polyploidization. Brit. J. of Haematol. 152 (4): 469–484. doi:10.1111/j.1365-2141.2010.08548.x. (Download PDF)
229. Tracy, BP, Jones, S.W. and Papoutsakis, ET. 2011. Inactivation of σE and σG in Clostridium acetobutylicum illuminates their roles in clostridial-cell form biogenesis, granulose synthesis, solventogenesis, and spore morphogenesis. J. Bacteriol. 193 (6): 1414–1426 (doi:10.1128/JB.01380-10). (Download PDF)
230. Jones, SW, Tracy, BP, Gaida, SM, and Papoutsakis, ET. 2011. Inactivation of σF in Clostridium acetobutylicum ATCC 824 blocks sporulation prior to asymmetric division, abolishes σE- and σG-protein expression, but does not block solvent formation. J. Bacteriol. 193 (10): 2429-2440 (doi:10.1128/JB.00088-11). (Download PDF)
231. Papoutsakis ET & Alsaker KV. Towards a Synthetic Biology of the Stress-Response and the Tolerance Phenotype. Book Chapter in: "Systems Metabolic engineering" (SY Lee and C. Whittmann, Eds), Springer (in press).
232. Bi, C, Jones, SW, Hess, DR,Tracy, BP, and Papoutsakis, ET. 2011. SpoIIE is necessary for asymmetric division, sporulation, and the expression of σF, σE, and σG, but does not control solvent production in Clostridium acetobutylicum. submitted.
233. Lindsey, S. and Papoutsakis, ET. 2011. The importance of physiologically inspired physicochemical parameters on hematopoietic stem-cell maintenance and lineage-specific differentiation in ex vivo cultures. Book chapter in: "Stem Cells - Mechanisms and Technologies" (M. K. Stachowiak & E. S. Tzanakakis, , Editors). World Scientific Publishing and Imperial College Press (in press). (Download PDF)
234. Panuganti S, Papoutsakis ET, Miller WM. 2010. "Three-stage ex vivo expansion of high-ploidy megakaryocytic cells inspired by the bone marrow niche”. (under revision).
235. Apostolidis, PA, Woulfe, DS, Chavez, M, Miller, WM and Papoutsakis, ET. Role of Tumor Suppressor P53 in Megakaryopoiesis and Platelet Function. Submitted. (Download PDF)