Patents

Sandstrom, C., Papoutsakis, E.T., Miller, W.M., and Bender, J.G. "Flow-through bioreactor with grooves for cell retention", US Patent No. 5,512,480, issued on April 30, 1996. (Click Here to Download US Patent Information)
Collins, P.C., E.T. Papoutsakis, and W.M. Miller. "Method of Determining Progenitor Cell Content of A Hematopoietic Cell Culture," U.S. Patent 6,077,708, issued on June 20, 2000. (Click Here to Download US Patent Information)
Papoutsakis, E.T, C. Tomas, M. Tesic, and J. Y. Santiago. "Increased cell resistance to toxic organic substances." US Patent No. 6,960,465, issued on Nov. 1, 2005. (Click Here to Download US Patent Information)
Papoutsakis, E.T., S.Y. Lee, and J.H. Park. "Method for preparing butanol through butyryl-CoA as an intermediate using bacteria." PCT/KR2007/006524 (Dec 14, 2007), WO2008072920-A1 (Jun 19, 2008). (Click Here to Download World Patent Information)
Lee, S.Y., J.H. Park, and E.T. Papoutsakis. "Enhanced butanol producing microorganisms and method for preparing butanol using the same." PCT/KR2007/006525 (Dec 14, 2007). WO2008072921-A1 (Jun 19, 2008). (Click Here to Download World Patent Information)
Lee, S.Y, Park, J.H, and Papoutsakis, E.T. "Preparing a recombinant mutant microorganism having high butanol productivity by deleting or attenuating a gene and introducing or amplifying the gene coding for an enzyme involved in butanol biosynthesis into the microorganism". WO2008072921-A1 (WOKR006525 ) (Dec 14, 2007), US875145P (Dec 15, 2006), US899201P (Feb 02, 2007).
Papoutsakis, E.T., Lee, S.Y., and Park, J.H. "Method for preparing butanol through butyryl-CoA as an intermediate using bacteria." WO2008072920-A1, WOKR006524 (Dec 14, 2007); US875145P (Dec 15, 2006); US899201P (Feb 02, 2007).
Lee, S.Y, Papoutsakis, E.T., and Jang, Y.S. Method for preparing butanol through butyryl-CoA as an intermediate using yeast. WO2008097064-A1 (WOKR000787). 11 Feb 2008 (US900,248P (08 Feb 2007.)
Senger, R.S., Papoutsakis, E.T. "Reverse Engineering Genome-Scale Metabolic Network Reconstructions for Organisms With Incomplete Genome Annotation and a Completed Network for the Solventogenic Clostridium Acetobutylicum ATCC 824," UD08-33 (April 11, 2008). Click to Download the Manuscript that relates to this patent. (Part 1) (Part 2)

Tracy, B.P. & Papoutsakis, E.T. "Recombinant Expression of Resolvase Proteins for Altering Bacterial Genomes and Facilitating Chromosomal Integration.” Filed May 8, 2008, U.S. Provisional Application No. 61/051,515 (NU28019).

Tracy, B.P., Paredes, C.J. & Papoutsakis, E.T. "Decoupling solvent and other product formation from sporulation by knocking out sigE and/or sigG in solventogenic or ethanol producing clostridia and other related endospore formers for enhanced and sustained bioprocessing using a variety of simple and complex carbohydrates.” Filed June 16, 2008, U.S. Provisional Application No. 61/061,845 (NU28026)

Papoutsakis, E.T. and R.S. Sillers. "Recombinant non-sporulating, non-degenerating, Clostridium acetobutylicum strains producing mostly butanol as solvent products suitable for continuous butanol production”. U.S. Provisional Patent filled Spring 2008. (NU28101). This patent is based on the attached manuscript. (Click Here to Download the Manuscript)

Sillers, R.S. and E.T. Papoutsakis. "Systems and Methods for Selective Alcohol Production”. Provisional US patent filled on July 22, 2008. US Provisional Application No. 61/082,753 (NU 28106). This patent is based on the attached manuscript. (Click Here to Download the Manuscript)